MTOR inhibitor-11 - CAS 3033409-32-1

MTOR inhibitor-11 (Compound 9) is a brain-penetrant compound that inhibits mTOR with an IC50 of 21 nM for pS6 and exhibits inhibitory activity against pCHK1 and PDE4D with IC50 values of 17.2 μM and 17.0 μM, respectively. This compound is utilized in CNS disease research [1].

MTOR

PI3K/Akt/mTOR signaling

3033376

C21H26N6O2

394.47

C[C@H]1N(C2=C3C(=NC(=C2)N4[C@@H](C)COCC4)N=C(N3)C5=CC=CC=N5)CCOC1

-20°C

Ice Packs

Small Compound