MTP - CAS 2377372-62-6

MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation. Further, it inhibits JAK2 signaling, rendering it useful for the study of oral squamous cell carcinoma [1].

Apoptosis, Reactive Oxygen Species, JAK, Autophagy

NF-κB, Immunology/Inflammation, Angiogenesis, Autophagy, Stem Cells, JAK/STAT signaling, Apoptosis, Metabolism, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic

2377304

C29H23F3N4O2

516.51

C(CC(NC)=O)C=1C=C(N(N1)C2=CC=C(NC(C#C)=O)C=C2)C3=CC=C(C=C3)C4=CC=C(C(F)(F)F)C=C4

-20°C

Ice Packs

Small Compound