MtTMPK-IN-2 - CAS 2799607-71-7

MtTMPK-IN-2 (compound 15), a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), demonstrates an IC50 value of 1.1 μM. This compound effectively inhibits Mtb H37Rv with a minimum inhibitory concentration (MIC) of 12.5 μM and exhibits cytotoxicity in MRC-5 human fibroblast cells with an EC50 of 6.1 μM. MtTMPK-IN-2 is valuable for tuberculosis research [1].

Others, DNA/RNA Synthesis, Antibacterial

Cell Cycle/Checkpoint, Others, Microbiology/Virology, DNA Damage/DNA Repair

2799529

C23H24ClN3O3

425.91

O=C1N(C2CCN(CC3=CC(OC4=CC(Cl)=CC=C4)=CC=C3)CC2)C=C(C)C(=O)N1

-20°C

Ice Packs

Small Compound