MtTMPK-IN-3 - CAS 2799607-80-8

MtTMPK-IN-3 (compound 25) is a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (MtTMPK) with an IC50 value of 0.12 μM. It also exhibits inhibitory activity against Mtb H37Rv with a MIC of 12.5 μM and shows cytotoxicity in MRC-5 human fibroblast cells (EC50 = 12.5 μM) . This compound is useful for tuberculosis research [1].

Antibacterial, Others, DNA/RNA Synthesis

DNA Damage/DNA Repair, Others, Microbiology/Virology, Cell Cycle/Checkpoint

2799519

C23H23Cl2N3O3

460.35

O=C1N(C2CCN(CC3=CC(OC4=CC(Cl)=CC(Cl)=C4)=CC=C3)CC2)C=C(C)C(=O)N1

-20°C

Ice Packs

Small Compound