MTX-23 - CAS 2488296-74-6

MTX-23, an AR-targeted Proteolysis Targeting Chimera (PROTAC), effectively degrades both AR-V7 and AR-FL, inhibiting the proliferation of CaP cells and inducing apoptosis [1].

Apoptosis, PROTACs, Androgen Receptor

Endocrinology/Hormones, Apoptosis, PROTAC

2488216

C43H53F2N7O7S2

882.05

O=C(NCCCCC(=O)N[C@@H](C(C)(C)C)C(=O)N1[C@@H](C[C@@H](O)C1)C(=O)N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)COC4=C(C=CC(F)=C4F)C5N=C(SC=5)N6CCOCC6

-20°C

Ice Packs

PROTAC