Multi-kinase-IN-2 - CAS 2095628-21-8

Multi-kinase-IN-2 is an orally active inhibitor of angiokinases. multi-kinase-IN-2 significantly inhibits the activity of angiokinases such as VEGFR-1/2/3, PDGFRα/β, FGFR-1, LYN and c-KIT kinases. -IN-2 significantly attenuates phosphorylation of AKT and ERK proteins, induces apoptosis and has anticancer effects.

Others, Apoptosis, FGFR, VEGFR, Akt, PDGFR, c-Kit, Src

Apoptosis, Angiogenesis, Others, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

2095599

C34H35N5O3

561.67

C(\NC1=CC=C(C=C1)N2C(CN3CCN(C)CC3)=CC=C2C)(=C\4/C=5C(NC4=O)=CC(C(OC)=O)=CC5)/C6=CC=CC=C6

-20°C

Ice Packs

Small Compound