Multi-kinase inhibitor 4 - CAS 2648279-77-8

Multi-kinase inhibitor 4 (compound 14) serves as an orally effective inhibitor targeting FLT1, KDR, FLT3, FLT4, PDGFRα, and PDGFRβ, exhibiting IC50 values of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, and 0.89 nM respectively. This compound plays a crucial role in cancer research.

FLT, PDGFR

Tyrosine Kinase/Adaptors, Angiogenesis

2648194

C25H24N6O2

440.5

O=C(NC=1ON=C(C1)C(C)(C)C)CC2=CC=C(C=C2)N3C=NC=4C=C(C=CC43)C=5C=NNC5

-20°C

Ice Packs

Small Compound