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Mutant IDH1-IN-3 - CAS 1648909-73-2

Mutant IDH1-IN-3 - CAS 1648909-73-2

MF-0112920-01

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Product Details

  • Bioactivity

    Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor targeting the mutant isocitrate dehydrogenase 1 (IDH1), with an IC50 of 13 nM for R132HIDH1. It effectively suppresses the production of D-2-hydroxyglutarate (2HG) in cells and is applicable for research in oncology.

  • Target

    Isocitrate Dehydrogenase (IDH)

  • Related Pathways

    Metabolism

  • CAS Number

    1648834

  • Molecular Formula

    C22H30N4O

  • Molecular Weight

    366.5

  • SMILES

    OC=1C(=CC(=CC1CN2C=NC=C2)C(C)(C)CC(C)(C)C)CN3C=NC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound