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Molfinity

Mutated EGFR-IN-3 - CAS 2375107-27-8

Mutated EGFR-IN-3 - CAS 2375107-27-8

MF-0023008-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    Mutated EGFR-IN-3 is a ATP-competitive and highly selective allosteric dibenzodiazepinone EGFR (L858R/T790M) and EGFR (L858R/T790M/C797S) inhibitor (IC50 of 12 nM and 13 nM, respectively.)

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    2375072

  • Molecular Formula

    C31H29FN4O2

  • Molecular Weight

    508.59

  • SMILES

    O=C1C2=CC(OC3=CC=C(C=C3)N4CCN(C)CC4)=CC=C2NC5=CC=C(F)C=C5N1CC=6C=CC=CC6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound