MW-150 hydrochloride - CAS 1923773-01-6

MW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a potent and selective inhibitor of p38α MAPK with a Ki value of 101 nM. It exhibits excellent CNS penetration and oral bioavailability, and effectively suppresses the phosphorylation of MK2, a substrate of endogenous p38α MAPK, in activated glial cells.

Autophagy, p38 MAPK, Others

Others, Autophagy, MAPK

1923773-01-6

C24H24ClN5

417.93

Cl.CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1

-20°C

Ice Packs

Small Compound