MY-673 - CAS 2944459-96-3

MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 protein expression in the TGF-β/SMAD pathway. This compound effectively reduces cell proliferation and migration while inducing apoptosis in both in vivo and in vitro settings [1].

Apoptosis, Others, ERK, Microtubule Associated, TGF-beta/Smad

Cytoskeletal Signaling, Stem Cells, Apoptosis, Others, MAPK

2944360

C18H14N2O4

322.31

O=C1CN(C=2C(=CC(OC)=CC2)N1)C=3C=4C(OC(=O)C3)=CC=CC4

-20°C

Ice Packs

Small Compound