Myosin-IN-1 - CAS 849011-39-8

Myosin-IN-1 (compound F10), a specific inhibitor of cardiac myosin, acts by stabilizing the cardiac myosin motor domain in its closed biochemical and structural state. It reduces myocardial force production and calcium sensitivity, functioning as a negative inotropic agent. In isolated Langendorff-perfused rat hearts, Myosin-IN-1 decreases stress in myofilaments and diminishes the development of left ventricular pressure. This compound is applicable in heart failure research [1].

Myosin

Cytoskeletal Signaling

849011-39-8

C12H16N4OS2

296.41

O=C1C2=C(SC(CC)=C2)N=CN1NC(NC(C)C)=S

-20°C

Ice Packs

Small Compound