Myricanone - CAS 32492-74-3

Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation by down-regulation of NF-ÎoB and STAT3 signalling cascades. Myricanone shows in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic activity using growth of flank organ in castrated Syrian hamsters and/or hair regrowth after shaving in testosterone-treated C57Black/6CrSlc mice.

HSP, Bcl-2 Family, NF-κB, Caspase, STAT, ROS, Endogenous Metabolite

NF-κB, Immunology/Inflammation, Cytoskeletal Signaling, Proteases/Proteasome, Stem Cells, JAK/STAT signaling, Metabolism, Apoptosis

32415

C21H24O5

356.41

COc1c(O)c2CCCCC(=O)CCc3ccc(O)c(c3)-c(c2)c1OC

-20°C

Ice Packs

Natural Product