MYX1715 - CAS 2445448-66-6

MYX1715 is an inhibitor of N-myristoyltransferase (NMT), exhibiting a KD of 0.09 nM. It inhibits the proliferation of LU0884 and LU2511, with IC50 values of 44 nM and 9 nM, respectively. In mouse models, MYX1715 demonstrates antitumor activity against neuroblastoma and gastric cancer. Additionally, MYX1715 can be utilized as a toxin in ADCs.

ADC Cytotoxin

Antibody-drug Conjugate/ADC Related

2445448-66-6

C25H29ClN6O2

480.99

O=C(C1=NN(C(=C1CCOC=2C=C(Cl)C=CC2C=3C=CC4=NC=C(N4C3)CCN)C)C)N(C)C

-20°C

Ice Packs

Small Compound