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Molfinity

N-Ac-γ-Calicheamicin-AcBut-NHS ester - CAS 174885-02-0

N-Ac-γ-Calicheamicin-AcBut-NHS ester - CAS 174885-02-0

SKU:MF-0112520-01

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  • Bioactivity

    AcBut-N-Ac-γ-Calicheamicin serves as a toxic molecule for ADCs, inducing cell cycle arrest and apoptosis (Apoptosis) by causing DNA double-strand breaks. Primarily utilized in the synthesis of antibody-drug conjugates (ADC), it holds promise for cancer research, particularly in studies related to acute lymphoblastic leukemia (ALL) and other hematological malignancies.

  • Target

    ADC Cytotoxin

  • Related Pathways

    Antibody-drug Conjugate/ADC Related

  • CAS Number

    174885-02-0

  • Molecular Formula

    C77H99IN6O28S3

  • Molecular Weight

    1779.73

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound