N-butyryl-L-Homoserine lactone-d5 - CAS 2701379-46-4

N-Butyryl-L-Homoserine lactone-d5 is a deuterated version of N-Butanoyl-L-homoserine lactone. Serving as a cleavable ADC linker, N-Butanoyl-L-homoserine lactone (C4-HSL) is employed in the synthesis of antibody-drug conjugates (ADCs) . This compound also exhibits antimicrobial activity, making it useful in combating bacterial biofilms. Additionally, N-Butanoyl-L-homoserine lactone aptamers are employed to inhibit quorum sensing and prevent the formation of Pseudomonas aeruginosa biofilms.

ADC Linker

Antibody-drug Conjugate/ADC Related

2701379-46-4

C8H13NO3

176.23

N(C(CC(C([2H])([2H])[2H])([2H])[2H])=O)[C@@H]1C(=O)OCC1

-20°C

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