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N-Depropylpropafenone - CAS 86383-21-3
N-Depropylpropafenone - CAS 86383-21-3
SKU:MF-0110809-01
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Product Details
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Bioactivity
N-Depropylpropafenone, an active metabolite of Propafenone, is produced through the metabolism by the CYP450 enzyme system (primarily CYP2D6) . It functions by blocking sodium ion channels, thereby delaying the depolarization process in myocardial cells and exhibiting antiarrhythmic properties.
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Target
Drug Metabolite, Sodium Channel
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Related Pathways
Metabolism, Membrane transporter/Ion channel
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CAS Number
86359
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Molecular Formula
C18H21NO3
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Molecular Weight
299.36
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SMILES
O=C(C=1C=CC=CC1OCC(O)CN)CCC=2C=CC=CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound