N-Descyclopropanecarbaldehyde Olaparib - CAS 763111-47-3

N-Descyclopropanecarbaldehyde Olaparib, an Olaparib analogue, incorporates a DOTA moiety. It acts as a CRBN-based ligand for the formation of novel dual EGFR and PARP PROTAC, DP-C-4[1]. N-Descyclopropanecarbaldehyde Olaparib is suitable for radiolabeling with F-18 or a fluorophore to visualize tumors using positron emission tomography (PET) or optical imaging[2].

E3 Ligase Ligand-Linker Conjugate, PARP, Ligands for Target Protein for PROTAC, Others

Chromatin/Epigenetic, Others, DNA Damage/DNA Repair, PROTAC

763111-47-3

C20H19FN4O2

366.39

Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCNCC1

-20°C

Ice Packs

PROTAC