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N-desmethyl Rosiglitazone - CAS 257892-31-2

N-desmethyl Rosiglitazone - CAS 257892-31-2

MF-0152379

$916.97 USD
$916.97 USD
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Product Details

  • Bioactivity

    N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.

  • Target

    Drug Metabolite, PPAR, Cytochromes P450, Others

  • Related Pathways

    Others, DNA Damage/DNA Repair, Metabolism

  • CAS Number

    257859

  • Molecular Formula

    C17H17N3O3S

  • Molecular Weight

    343.4

  • SMILES

    O=C1NC(=O)C(Cc2ccc(OCCNc3ccccn3)cc2)S1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound