N-Formyl-Met-Leu-Phe-Lys - CAS 67247-11-4

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide that acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM for FPR1, 6.7 μM for FPR2, and 0.88 μM for FPR2-D2817.32G. This chemotactic peptide binds specifically to receptors on leukocyte membranes and its uptake can contribute to the quantitative assessment of neutrophils in localized inflammatory processes, independent of associated edema formation or microcirculatory compromise.

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67232

0.997

C27H43N5O6S

565.73

[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](CCSC)NC=O)=O)CC(C)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O

-20°C

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Peptide