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N-myristoyl-RKRTLRRL - CAS 152246-40-7
N-myristoyl-RKRTLRRL - CAS 152246-40-7
SKU:MF-0158089-01
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Product Details
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Bioactivity
N-myristoyl-RKRTLRRL is a compound that impedes the binding of protein kinase C (PKC) substrates and inhibits calcium (Ca2+) - and phosphatidylserine (PS) -dependent phosphorylation of histones, exhibiting an IC50 of 5 μM. Additionally, it demonstrates an inhibitory effect on histone phosphorylation with an IC50 of 80 μM [1] [2].
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Target
PKC
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Related Pathways
Chromatin/Epigenetic, Cytoskeletal Signaling
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CAS Number
152199
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Molecular Formula
C60H117N21O11
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Molecular Weight
1308.71
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SMILES
[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCNC(=N)N)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCCCCCC)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCNC(=N)N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide