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N, N-Dimethylsphingosine - CAS 119567-63-4
N, N-Dimethylsphingosine - CAS 119567-63-4
SKU:MF-0044775-01
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$272.01 USD
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$272.01 USD
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Product Details
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Bioactivity
N, N-Dimethylsphingosine, an endogenous metabolite, is a potent competitive sphingosine kinase (SphK) inhibitor that selectively inhibits sphingosine phosphorylation without affecting its N-acylation.DMS is elevated in models of neuropathic pain, and may mediate mechanical nociception by increasing the release of IL-1β and MCP-1.
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Target
S1P Receptor
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Related Pathways
GPCR/G Protein
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CAS Number
119500
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Molecular Formula
C20H41NO2
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Molecular Weight
327.55
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SMILES
CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)N(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound