N'-Nitrosonornicotine - CAS 80508-23-2

N'-Nitrosonornicotine is a tobacco-specific N-nitrosamine and carcinogen that has been found in unburned tobacco and cigarette smoke.1It induces the formation of DNA adducts in isolated rat nasal mucosa and esophagus. N'-Nitrosonornicotine induces tumor formation in rat esophagus and nasal cavity, mouse lung, forestomach, and trachea, and hamster trachea and forebrain. Urinary levels of N'-nitrosonornicotine are positively correlated with the risk of esophageal cancer in smokers.2

Others, Drug Metabolite

Metabolism, Others

80483

C9H11N3O

177.207

O=NN1CCCC1c1cccnc1

-20°C

Ice Packs

Small Compound