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N, O-Didansyl-L-tyrosine cyclohexylammonium - CAS 102783-47-1
N, O-Didansyl-L-tyrosine cyclohexylammonium - CAS 102783-47-1
SKU:MF-0156300-01
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Product Details
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Bioactivity
N, O-Didansyl-L-tyrosine cyclohexylammonium is a potent and selective inhibitor of thymidylate synthase (TS), showing activity against TS in Escherichia coli, Lactobacillus casei, and humans, with IC50 values of 5.0, 3.4, and 119 μM, respectively [1].
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Target
DNA/RNA Synthesis
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Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
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CAS Number
102735
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Molecular Formula
C39H46N4O7S2
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Molecular Weight
746.94
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SMILES
NC1CCCCC1.CN(C)c1cccc2c(cccc12)S(=O)(=O)N[C@@H](Cc1ccc(OS(=O)(=O)c2cccc3c(cccc23)N(C)C)cc1)C(O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide