N-Oleoyl-L-Serine - CAS 107743-37-3

N-Oleoyl-L-Serine (N-Oleoylserine) is an endogenous long-chain fatty acid amide that is a lipid modulator of bone remodeling and stimulates osteoclast apoptosis which can be used to study osteoporosis. N-Oleoyl-L-Serine showed high activity in an osteoblast proliferation assay.N-Oleoyl-L-Serine promotes osteoclast apoptosis by inhibiting Erk1/2 phosphorylation and expression of nuclear κB ligand (RANKL) receptor activator in bone marrow stromal cells and osteoblasts, which attenuates osteoclast populations.

Apoptosis

Apoptosis

107703

0.9976

C21H39NO4

369.54

N([C@H](C(O)=O)CO)C(CCCCCCC/C=C\CCCCCCCC)=O

-20°C

Ice Packs

Peptide