N-Sterol - CAS 3069417-18-8

N-Sterol is a sterol lipid employed in the formation of lipid nanoparticles (LNP) for delivering mRNA both in vitro and in vivo. N-Sterol LNPs are absorbed by J774A.1 macrophages in a manner dependent on lipid composition, involving clathrin-coated pits, caveolin-mediated endocytosis, micropinocytosis, or phagocytosis at varying frequencies.

Liposome

Metabolism

3069417-18-8

C34H57NO3

527.82

C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C[C@@H](OC(C=CN(CCOC)C)=O)CC2)[H])[H]

-20°C

Ice Packs

Inhibitors & Agonists