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NAE-IN-M22 - CAS 864420-54-2

NAE-IN-M22 - CAS 864420-54-2

SKU:MF-0018381-01

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  • Bioactivity

    NAE-IN-M22 (NEDD8 inhibitor M22) is a selective, potent and reversible inhibitor of NEDD8 activating enzyme (NAE) . NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.

  • Target

    Apoptosis, E1/E2/E3 Enzyme

  • Related Pathways

    Apoptosis, Ubiquitination

  • CAS Number

    864364

  • Purity

    0.9867

  • Molecular Formula

    C20H24Cl2N2

  • Molecular Weight

    363.32

  • SMILES

    Clc1ccc(CCNC2CCN(Cc3ccccc3)CC2)c(Cl)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound