Nafamostat - CAS 81525-10-2

Nafamostat is a synthetic serine protease inhibitor and an anticoagulant used in haemodialysis. It induces apoptosis by upregulating TNFR1 expression, inhibits NF-κB activity by blocking IκBα phosphorylation, and can also inhibit SARS-CoV-2 and COVID-19.

Serine Protease, SARS-CoV, Apoptosis, NF-κB, Anti-infection, TNF

Microbiology/Virology, Apoptosis, Proteases/Proteasome, NF-κB

81513

C19H17N5O2

347.37

O=C(OC=1C=CC2=CC(=CC=C2C1)C(=N)N)C3=CC=C(C=C3)NC(=N)N

-20°C

Ice Packs

Small Compound