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Naldemedine - CAS 916072-89-4
Naldemedine - CAS 916072-89-4
SKU:MF-0141924-01
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Product Details
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Bioactivity
Naldemedine (S 297995) is a peripheral selective μ-opioid receptor antagonist being developed by Shionogi for the treatment of opioid-induced adverse reactions, including constipation, nausea, and vomiting. They are usually well tolerated, mainly with mild to moderate gastrointestinal side effects.
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Target
Others, Opioid Receptor
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Related Pathways
GPCR/G Protein, Endocrinology/Hormones, Others, Neuroscience
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CAS Number
915979
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Molecular Formula
C32H34N4O6
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Molecular Weight
570.64
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SMILES
O[C@]12[C@@]34C=5C(O[C@]3(C(O)=C(C(NC(C)(C)C6=NC(=NO6)C7=CC=CC=C7)=O)C1)[H])=C(O)C=CC5C[C@]2(N(CC8CC8)CC4)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound