Nampt activator-3 - CAS 2790481-63-7

NAMPT Activator-3, a derivative of NAT, is a potent activator of NAMPT, demonstrating an EC50 of 2.6 μM and KD of 132 nM. It effectively shields cultured cells against toxicity induced by FK866 and has demonstrated significant neuroprotective effects in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model, without any apparent toxicity [1].

NAMPT, Others

Others, Metabolism

2790411

C19H20N2O3

324.37

O(CC(NC1=CC=C(O)C=C1)=O)C2=C(C(C)(C)C)C=CC=C2C#N

-20°C

Ice Packs

Small Compound