Nampt-IN-16 - CAS 3077970-44-3

Nampt-IN-16 (Compound 9a) is an orally active NAMPT inhibitor with an IC50 of 0.15 μM. It reduces intracellular NAD+ and ATP levels. Nampt-IN-16 inhibits the proliferation, migration, and invasion of gastric cancer cells, induces cell cycle arrest and apoptosis, and alters cellular metabolism. This compound is applicable for research in tumors such as gastric cancer.

Apoptosis, NAMPT

Metabolism, Apoptosis

3077923

C25H25FN4O3

448.49

O=C(OCC=1C=NC=CC1)NC2=CC=C(C=C2)CNC(=O)C3=CC(F)=CC=C3N4CCCC4

-20°C

Ice Packs

Small Compound