Nanatinostat - CAS 1256448-47-1

Nanatinostat (CHR-3996) is an HDAC inhibitor with selectivity and oral bioavailability, with IC50 values of 3-7 nM for HDAC1/2/3 and >200 nM for other subtypes. Nanatinostat also inhibits tumour cell proliferation and induces apoptosis, for studying neurodegenerative diseases and cancer.

Apoptosis, HDAC

Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis

1256400

0.9903

C20H19FN6O2

394.4

N(CC1=NC2=C(C=C1)C=C(F)C=C2)[C@H]3[C@]4([C@@]3(CN(C4)C=5N=CC(C(NO)=O)=CN5)[H])[H]

-20°C

Ice Packs

Small Compound