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NAP1051 - CAS 864516-77-8
NAP1051 - CAS 864516-77-8
SKU:MF-0122591-01
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Product Details
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Bioactivity
NAP1051, a biomimetic analog of Lipoxin A4, serves an anti-tumor role by targeting the inflammatory tumor microenvironment. It inhibits the chemotaxis of neutrophils to fMLP and stimulates macrophage efferocytosis by activating AKT. NAP1051 is utilized in research on colorectal cancer.
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Target
Akt
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Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
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CAS Number
864516-77-8
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Molecular Formula
C23H34O5
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Molecular Weight
390.51
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SMILES
C(=C/[C@H]([C@H](CCCC(OC)=O)O)O)\C1=CC(/C=C/[C@@H](CCCCC)O)=CC=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound