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Naphthablin - CAS 167568-51-6
Naphthablin - CAS 167568-51-6
SKU:MF-0123725-01
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Product Details
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Bioactivity
Naphthablin is a naphthoquinone compound that inhibits the function of the Abl oncogene. It prevents the morphological transformation of v-ablts-NIH3T3 cells induced by Abl and also suppresses RNA synthesis.
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Target
Bcr-Abl, DNA/RNA Synthesis
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Related Pathways
Angiogenesis, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair
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CAS Number
167568-51-6
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Molecular Formula
C29H36O8
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Molecular Weight
512.591
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SMILES
O=C1C=2[C@]3([C@@](C(C)(C)OC2C(=O)C=4C1=CC(O)=C(C(C=C)(CO)C)C4O)(C[C@H](OC(C(C)C)=O)[C@H](C)C3)[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product