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Naphthablin - CAS 167568-51-6

Naphthablin - CAS 167568-51-6

SKU:MF-0123725-01

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  • Bioactivity

    Naphthablin is a naphthoquinone compound that inhibits the function of the Abl oncogene. It prevents the morphological transformation of v-ablts-NIH3T3 cells induced by Abl and also suppresses RNA synthesis.

  • Target

    Bcr-Abl, DNA/RNA Synthesis

  • Related Pathways

    Angiogenesis, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair

  • CAS Number

    167568-51-6

  • Molecular Formula

    C29H36O8

  • Molecular Weight

    512.591

  • SMILES

    O=C1C=2[C@]3([C@@](C(C)(C)OC2C(=O)C=4C1=CC(O)=C(C(C=C)(CO)C)C4O)(C[C@H](OC(C(C)C)=O)[C@H](C)C3)[H])[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product