Naphthofluorescein - CAS 61419-02-1

Naphthofluorescein (Naphthafluorescein) is a Mint3 inhibitor with potential antitumor and anti-inflammatory activities, inhibits the interaction between HIF-1 and Mint3, inhibits Mint3-dependent HIF-1 activity, and inhibits glycolytic activity in cancer cells and macrophages without showing significant in vitro cytotoxicity or in vivo side effects. Naphthofluorescein is also a fluorescent pH-sensitive probe for functional Cherenkov imaging.

HIF/HIF Prolyl-Hydroxylase, HIF

Angiogenesis, Chromatin/Epigenetic, Metabolism

61419-02-1

0.9934

C28H16O5

432.42

Oc1ccc2c3Oc4c(ccc5cc(O)ccc45)C4(OC(=O)c5ccccc45)c3ccc2c1

-20°C

Ice Packs

Dye-Reagents