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Naquotinib - CAS 1448232-80-1
Naquotinib - CAS 1448232-80-1
SKU:MF-0018539-01
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Product Details
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Bioactivity
Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.
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Target
EGFR
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Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
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CAS Number
1448151
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Purity
0.9749
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Molecular Formula
C30H42N8O3
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Molecular Weight
562.71
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SMILES
CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1O[C@@H]1CCN(C1)C(=O)C=C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound