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Naquotinib - CAS 1448232-80-1

Naquotinib - CAS 1448232-80-1

SKU:MF-0018539-01

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  • Bioactivity

    Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    1448151

  • Purity

    0.9749

  • Molecular Formula

    C30H42N8O3

  • Molecular Weight

    562.71

  • SMILES

    CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1O[C@@H]1CCN(C1)C(=O)C=C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound