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Naquotinib mesylate - CAS 1448237-05-5

Naquotinib mesylate - CAS 1448237-05-5

SKU:MF-0023034

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  • Bioactivity

    Naquotinib mesylate (ASP8273 (mesylate) ) is an orally available, mutant-selective and irreversible inhibitor of EGFR (iC50s of 8-33 nM and 230 nM for toward EGFR mutants and EGFR) .

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    1448237-05-5

  • Molecular Formula

    C31H46N8O6S

  • Molecular Weight

    658.81

  • SMILES

    CS(O)(=O)=O.CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1O[C@@H]1CCN(C1)C(=O)C=C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound