Naroparcil - CAS 120819-70-7

Naroparcil, an orally available thioglycoside analog of 4-methylumbelliferyl β-D-xyloside, showed antithrombotic effects in the Wessler sludge model of venous thrombosis (jugular vein) .Naroparcil enhanced the formation of the thrombin/heparin cofactor II complex, induced dermatophyte sulfate-like substances in plasma from treated rabbits appearance, but reduced the formation of thrombin/antithrombin III complexes in plasma incubated with (125I) -human alpha-thrombin.

Factor Xa, Thrombin

Metabolism, Proteases/Proteasome

120742

0.9999

C19H17NO4S2

387.47

S(C1=CC=C(C(=O)C2=CC=C(C#N)C=C2)C=C1)[C@H]3[C@H](O)[C@@H](O)[C@H](O)CS3

-20°C

Ice Packs

Small Compound