Nav1.1 activator 1 - CAS 2332897-85-3

Nav1.1 activator 1 (compound 4) is an effective Nav1.1 agonist with blood-brain barrier permeability, exhibiting significant selectivity for Nav1.2, Nav1.5, and Nav1.6. It increases the decay time constant of Nav1.1 at 0.03 μM current and can be used for studying central nervous system disorders.

Sodium Channel

Membrane transporter/Ion channel

2332809

C24H23F3N4O

440.46

C(NC=1C=CC(C(C)C)=NC1)(=O)C=2C(=CC=NC2N3C[C@@H](F)CC3)C4=C(F)C=CC(F)=C4

-20°C

Ice Packs

Small Compound