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Nazartinib - CAS 1508250-71-2

Nazartinib - CAS 1508250-71-2

MF-0017409-01

$33.17 USD
$33.17 USD
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Product Details

  • Bioactivity

    Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    1508177

  • Purity

    0.9962

  • Molecular Formula

    C26H31ClN6O2

  • Molecular Weight

    495.02

  • SMILES

    CN(C)C\C=C\C(=O)N1CCCC[C@H](C1)n1c(NC(=O)c2ccnc(C)c2)nc2cccc(Cl)c12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound