Nazartinib mesylate - CAS 1508250-72-3

Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222/min on EGFR (L858R/790M) mutant) .

Others, EGFR

Angiogenesis, Tyrosine Kinase/Adaptors, Others, JAK/STAT signaling

1508175

C27H35ClN6O5S

591.12

S(C)(=O)(=O)O.N(C(=O)C=1C=C(C)N=CC1)C=2N(C=3C(N2)=CC=CC3Cl)[C@]4(CN(C(/C=C/CN(C)C)=O)CCCC4)[H]

-20°C

Ice Packs

Small Compound