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Molfinity

NB-360 - CAS 1262857-73-7

NB-360 - CAS 1262857-73-7

MF-0013718-01

$116.00 USD
$116.00 USD
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Product Details

  • Bioactivity

    NB-360 is a potent and brain-penetrable inhibitor of BACE1 and BACE2 with IC50s of 5, 5, and 6 nM for mouse and human BACE1 and BACE2. NB-360 exhibits excellent selectivity over the related aspartyl proteases pepsin, cathepsin E, and cathepsin D.

  • Target

    Beta-Secretase, BACE

  • Related Pathways

    Neuroscience

  • CAS Number

    1262777

  • Purity

    0.9972

  • Molecular Formula

    C21H19F4N5O2

  • Molecular Weight

    449.4

  • SMILES

    Cc1cc(cnc1C(=O)Nc1ccc(F)c(c1)[C@]1(C)CO[C@](C)(C(N)=N1)C(F)(F)F)C#N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound