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NBI-961 - CAS 2225902-98-5
NBI-961 - CAS 2225902-98-5
SKU:MF-0158980-01
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Product Details
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Bioactivity
NBI-961, a potent NEK2 inhibitor, suppresses proteasomal degradation and effectively induces G2/mitosis arrest and apoptosis within diffuse large B cell lymphoma (DLBCL) cells [1].
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Target
Apoptosis, Others, MAPK, Serine Protease
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Related Pathways
Apoptosis, Others, Proteases/Proteasome, MAPK
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CAS Number
2225902-98-5
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Molecular Formula
C28H27F3N6O2S
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Molecular Weight
568.61
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SMILES
O=C(N)C=1SC(=CC1OC(C=2C=CC=CC2C(F)(F)F)C)C3=CN=C4C=C(C=CN43)C=5C=NN(C5)CCN(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound