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NBTIs-IN-5 - CAS 2767443-78-5

NBTIs-IN-5 - CAS 2767443-78-5

SKU:MF-0044609-01

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  • Bioactivity

    NBTIs-IN-5 (Compound 5r) is a novel bacterial topoisomerase inhibitor (NBTI) DNA gyrase inhibitor that acts on Mycobacterium abscessus (Mabs) DNA procyclase (IC50: 1.5 μM), showing inhibitory effects on the growth of Mabsbamboo bacteria (MIC90: 0.4 μM) .

  • Target

    Others, Antibacterial

  • Related Pathways

    Others, Microbiology/Virology

  • CAS Number

    2767360

  • Molecular Formula

    C24H25F3N4O2

  • Molecular Weight

    458.48

  • SMILES

    N(C(=O)[C@@H]1CC[C@@H](NCC2=CC=C(C(F)(F)F)C=C2)CC1)C=3C4=C(C=CC(OC)=N4)N=CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound