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Molfinity

NCG21 - CAS 1079821-35-4

NCG21 - CAS 1079821-35-4

SKU:MF-0048617-01

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  • Bioactivity

    NCG21 is a GPR120 agonist, which showed potent extracellular signal-regulated kinase (ERK) activation in a cloned GPR120 system. NCG21 potently activated ERK, intracellular calcium responses and GLP-1 secretion in murine enteroendocrine STC-1 cells that express GPR120 endogenously. Administration of NCG21 into the mouse colon caused an increase in plasma GLP-1 levels.

  • Target

    Others, GPCR

  • Related Pathways

    Others, GPCR/G Protein, Endocrinology/Hormones

  • CAS Number

    1079782

  • Molecular Formula

    C23H24N2O3

  • Molecular Weight

    376.45

  • SMILES

    O=C(O)CCCC1=CC=C(OCCN(C2=NC=CC=C2)C=3C=CC=CC3)C=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound