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NCGC00029283 - CAS 714240-31-0

NCGC00029283 - CAS 714240-31-0

MF-0019379-01

$60.83 USD
$60.83 USD
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Product Details

  • Bioactivity

    NCGC00029283 is a potent inhibitor of Werner syndrome helicase-nuclease (WRN), displaying inhibitory activity against WRN helicase with an IC 50 value of 2.3 μM. Additionally, it exhibits inhibitory effects on Bloom syndrome protein helicase (BLM) and Fanconi anemia group J protein helicase (FANCJ) with IC 50 values of 12.5 μM and 3.4 μM, respectively.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    Cell Cycle/Checkpoint, DNA Damage/DNA Repair

  • CAS Number

    714209

  • Purity

    0.9984

  • Molecular Formula

    C18H12FN3O3

  • Molecular Weight

    337.3

  • SMILES

    COc1ccc2[nH]c(=O)c(cc2c1)-c1noc(n1)-c1ccc(F)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound