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NCT-502 - CAS 1542213-00-2

NCT-502 - CAS 1542213-00-2

MF-0033606-01

$34.67 USD
$34.67 USD
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Product Details

  • Bioactivity

    NCT-502 (N- (4,6-dimethylpyridin-2-yl) -4-[5- (trifluoromethyl) pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.

  • Target

    Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    1542213-00-2

  • Purity

    0.996

  • Molecular Formula

    C18H20F3N5S

  • Molecular Weight

    395.45

  • SMILES

    Cc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound