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Molfinity

NCT-503 - CAS 1916571-90-8

NCT-503 - CAS 1916571-90-8

SKU:MF-0015197-01

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  • Bioactivity

    NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=2.5 μM) with no activity against other dehydrogenases. NCT-503 has antitumor activity and inhibits the growth of PHGDH-dependent tumors.

  • Target

    TAM Receptor, FLT, Dehydrogenase

  • Related Pathways

    Metabolism, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    1916473

  • Purity

    0.9984

  • Molecular Formula

    C20H23F3N4S

  • Molecular Weight

    408.48

  • SMILES

    Cc1cc(C)nc(NC(=S)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound