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Molfinity

NCT-58 - CAS 2411429-33-7

NCT-58 - CAS 2411429-33-7

MF-0015031-01

$38.41 USD
$38.41 USD
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Product Details

  • Bioactivity

    NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR) . NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of Akt phosphorylation. NCT-58 kills Trastuzumab-resistant breast cancer stem-like cells. NCT-58 induces apoptosis in HER2-positive breast cancer cells.

  • Target

    Apoptosis, HSP

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling, Metabolism

  • CAS Number

    2411389

  • Purity

    0.996

  • Molecular Formula

    C27H34N2O5

  • Molecular Weight

    466.57

  • SMILES

    COc1cc(NC(=O)c2ccc3OC(C)(C)C=Cc3c2OC)ccc1OCCC1CCCCN1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound