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NCT02 - CAS 790245-61-3
NCT02 - CAS 790245-61-3
SKU:MF-0036806
Regular price
$53.35 USD
Regular price
$37.70 USD
Sale price
$53.35 USD
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Product Details
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Bioactivity
NCT02 is a molecular glue degrader targeting CDK12 and CCNK (cyclin K), inducing CCNK ubiquitination and inhibiting CRC cell proliferation in vivo and in vitro, leading to apoptosis and cell cycle arrest. It is intended for the investigation of metastatic colorectal cancer (CRC) .
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Target
Others, Molecular Glues, CDK
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Related Pathways
Others, Cell Cycle/Checkpoint, PROTAC
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CAS Number
790245-61-3
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Molecular Formula
C17H16N2O2S
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Molecular Weight
312.39
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SMILES
Cc1cnc(NC(=O)Cc2coc3cc4CCCc4cc23)s1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound